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Wednesday, August 5, 2020 | History

2 edition of Phenytoin-induced teratology and gingival pathology found in the catalog.

Phenytoin-induced teratology and gingival pathology

Phenytoin-induced teratology and gingival pathology

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  • 10 Currently reading

Published by Raven Press in New York .
Written in English

    Subjects:
  • Phenytoin -- Side effects.,
  • Fetus -- Effect of drugs on.,
  • Teratogenic agents.,
  • Gingival hyperplasia.,
  • Gums -- Effect of drugs on.,
  • Abnormalities, Drug-induced.,
  • Gingiva -- Drug effects.,
  • Gingival hyperplasia -- Chemically induced.,
  • Phenytoin -- Adverse effects.

  • Edition Notes

    Includes bibliographical references and index.

    Statementeditors, Thomas M. Hassell, Malcolm C. Johnston, Kenneth H. Dudley.
    ContributionsHassell, Thomas M., Johnston, M. C., Dudley, Kenneth H.
    Classifications
    LC ClassificationsRA1242.P54 P47
    The Physical Object
    Paginationxii, 240 p. :
    Number of Pages240
    ID Numbers
    Open LibraryOL4430270M
    ISBN 100890044120
    LC Control Number79062972

    might be the cause of the gingival side effect. 11,12 In , Brandon hypothesized that phenytoin had a direct action on the gingival tissues In , Angelopoulos argued that phenytoin induced degranulation of mast cells which resulted in the generation of a substance that increased collagen formation Larmas, in , suggested that. An increase in size of the gingiva is a common feature of gingival disease. The accepted current terms for this condition are gingival enlargement and gingival overgrowth. These are strictly clinical descriptive terms, and they avoid the erroneous pathologic connotations of terms used in the past, such as hypertrophic gingivitis and gingival hyperplasia.

    Phenytoin Induced Stevens Johnson Syndrome S Research Article. Int. J. Pharm. Sci. Rev. Res., 31(2), March – April ; Article No. 23, Pages: ISSN – X International Journal of Pharmaceutical Sciences Review and Research Available online at File Size: KB. Phenytoin induced gingival enlargement is seen in IL-6 and IL- 8 by fibroblasts [8]. Another most important almost % of patients. Clinically, gingival link was noticed between systemic fibrotic diseases to overgrowth usually starts from papillary region. Gingival gingival growth is the presence of myofibroblasts in.

    Book reviews. The Psychosurgery Debate (1 June, ) John R Phenytoin-Induced Teratology and Gingival Pathology (1 June, ) EH Reynolds. High Velocity Missile Wounds (1 June, ) H Alan Crockard. Management of Acute Head Injuries (1 June, ) Graham Teasdale. This banner text can have markup.. web; books; video; audio; software; images; Toggle navigation.


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Phenytoin-induced teratology and gingival pathology Download PDF EPUB FB2

Additional Physical Format: Online version: Phenytoin-induced teratology and gingival pathology. New York: Raven Press, © (OCoLC) Document Type.

Gingival Metabolism of Phenytoin and Covalent Binding of Its Reactive Metabolite to Gingival Proteins in the Rat. In book: Phenytoin-Induced Teratology and Gingival Pathology, Publisher: Raven.

TY - CHAP. T1 - Folic acid and phenytoin metabolism. AU - Vogel, Richard. PY - Y1 - M3 - Chapter (peer-reviewed) BT - Phenytoin induced teratology and gingival pathologyAuthor: Richard Vogel. EMT has been implicated in phenytoin-induced gingival overgrowth development, 5,19 and high epithelial expression of mesenchymal proteins in phenytoin-induced overgrowth observed here is of considerable interest.

Several markers of EMT were studied, including TGF-β1, E-cadherin, Ccn2, and by: 7. Sorry, our data provider has not provided any external links therefor we are unable to provide a : Paul R.

Kamen. The incidence rate of phenytoin-induced gingival overgrowth ranges from 3% to 93%, but 50% of patients on long-term therapy are prone to develop gingival overgrowth. This drug-induced overgrowth is noticed initially in the papillary region and during the course of the process involves the margins and the gingival by: 2.

In: Hassell TM, Johnston MC, Dudley KH, Brown et al. ORAL SURG ORAL MED ORAL PATHOL November eds. Phenytoin-induced teratology and gingival pathology. New Cited by: Considering the similar clinical and histopathologic features of CyA- and phenytoin-induced gingival hyperplasia, it would appear that the action of CyA is primarily on fibroblasts.

In this regard, it would be of interest to repeat certain phenytoin experiments conceived by Shafer,12 Liu and Bhatnagar," and others,14"17 substituting CyA for Cited by: Staple PH () Phenytoin-induced gingival overgrowth in the stump-tailed macaque (M.

arctoides): a new animal model. In: Hassell TM, Johnston MC, Dudley KH (eds) Phenytoin-induced teratology and gingival pathology.

Raven, New York Google ScholarCited by: 4. Pathogenesis of phenytoin-induced gingival l mechanisms are involved in the development of gingival overgrowth. Phenytoin induces a decrease in the Ca 2+ cell influx leading to a reduction in the uptake of folic acid, thus limiting the production of active collagenase.

The drug decreases collagen endocytosis through induction of a lower expression of 𝛼 2 𝛽 1-integrin by Cited by: Phenytoin-induced gingival overgrowth (PIGO) is a common complication of the continuous use of medications.

This paper presents a case of PIGO hindering oral function and compromising oral hygiene and aesthetics, which was treated with a combination of nonsurgical and surgical periodontal therapies. Several immunosuppressive agents are associated with many undesired side-effects involving oral tissue alterations [1,2].Drug-induced gingival overgrowth (DIGO) is the most commonly encountered side effect of a plethora of medications [], showing a high prevalence in response to calcineurin inhibitors such as cyclosporine-A [4,5,6].The severity of gingival hyperplasia clinical manifestation is Cited by: 1.

Phenytoin induced gingival enlargement: a case report. International Journal of Contemporary Medicine Surgery and Radiology. ;1(1) Introduction Gingival enlargement or gingival overgrowth are the current terms for all medication-related gingival lesions. Rama Univ J Dent Sci ;2(2) Phenytoin induced gingival enlargement 41 gingiva to specific exaggerated inflammatory reactions as in gingival overgrowth.7 The growth starts as a painless, bead-like enlargement of the interdental papilla, and extends to the facial and lingual gingival Size: KB.

Mohan RP, Rastogi K, Bhushan R, Verma S. Phenytoin-induced gingival enlargement: a dental awakening for patients with epilepsy. BMJ Case Rep. Apr Dhingra K, Prakash S. Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report. Gerodontology.

Jun. 29(2):e Define phenytoin-related gingival hyperplasia. phenytoin-related gingival hyperplasia synonyms, phenytoin-related gingival hyperplasia pronunciation, phenytoin-related gingival hyperplasia translation, English dictionary definition of phenytoin-related gingival hyperplasia.

Wells PG, Harbison RD () Significance of the phenytoin reactive arene oxide intermediate, its oxepin tautomer, and clinical factors modifying their roles in phenytoin-induced teratology.

In: Hassell TM, Johnston MC, Dudley KH (eds) Phenytoin-induced teratology and gingival pathology. Raven, New York, pp 83– Google ScholarCited by: 3 Book 3 Other report 2 Comment/debate 2 Editorial 2 Other contribution 1 Conference contribution 9 results Publication Year, Title (descending) Publication Year, Title (ascending) Title; Type; Filter Chapter (peer-reviewed) Psychiatric disorders in old age: Implication for the dental practioner.

Drug induced gingival enlargement. Presented by Guru Ram Tej K Postgraduate Mamata dental college 2. INTRODUCTION CLASSIFICATION PREVALENCE MEASUREMENT OF ENLARGEMENT DRUGS CAUSING ENLARGEMENT ANTI CONVULSANTS Pharmaco-dyanamics of anti epileptic drugs Pharmaco kinetics of phenytoin Pathogenesis of phenytoin induced gingival.

Pharmacological studies on the potentiation of phenytoin teratogenicity by acetaminophen. Authors. Joseph T. Lum, Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada M5S 1A1; Search for more papers by this author.

Lum was the recipient of an Ontario Graduate Scholarship. The present report describes treatment of a dog with generalized gingival enlargement and serves as a review of etiology and treatment options for this condition.

The combined use of scalpel blade, Cited by: A meta description is an HTML tag in the HTML code of your website, which allows you to customize a section of text that describes the page itself.

It plays a role in how your page is seen by search engine crawlers, and how it appears in SERPs.Arch Dermatol ; –5.

5 Allam JP, Paus T, Reichel C et al. DRESS syndrome associated with carbamazepine and phenytoin. Eur J Dermatol ; – 6 Mendiratta V, Bhushan P. Phenytoin-induced DRESS with cross-reactivity to carbamazepine in a year-old Indian child.